Canonical clock genes are present in the rat olfactory bulb (OB). (A) PCR results amplifying cDNA from rat OB and primers as reported by Kamphuis et al. (2005). Messenger RNAs encoding Clock, Bmal1, Period1–3(Per1–3), Cryptochrome1–2(Cry1–2), Reverb α, Rev-erb β, and retinoid-related orphan receptorα (RORα) are present in OB samples. (B) Line plot of Per2 mRNA changes over 48-h. N = 4–5 animals per time point. Points represent mean plus or minus standard error of the mean (SEM) in this and subsequent figures. Gray bars represent dark phases and white bars represent light phases. Per2 mRNA changes were statistically significant across the 48-h and for the second 24-h period (Kruskal–Wallis H test, P < 0.05) but not rhythmic across either 24-h tested (harmonic regression analysis, P > 0.05). Per2 mRNA was statistically significant for JTK_CYCLE analysis only for the second 24-h period (P < 0.05).