Table 2.
PCR success rates and agreement of genotyping outcomes in field samples
| RDT PCR success rates N = 121 (%; CI 95%) | Filter paper PCR success rates N = 121 (%; CI 95%) | Kappa value | |
|---|---|---|---|
|
Pfcrt K76T |
114 (94.2; 89.9-98.5) |
104 (86.0; 79.6-92.3) |
0.72 |
|
Pfmdr1 N86Y |
112 (92.6; 87.8-97.4) |
109 (90.1; 84.6-95.5) |
0.85 |
|
Pfmdr1 Y184F |
110 (90.9; 85.7-96.2) |
107 (88.4; 82.6-94.3) |
0.74 |
|
Pfmdr1 D1246Y |
113 (93.4; 88.8-97.9) |
107 (88.4; 82.6-94.3) |
0.77 |
| Pfmdr1 copy number | 84 (69.4; 61.0-77.8) | 77 (63.6; 54.9-72.4) | - |
Analyses of single nucleotide polymorphisms and pfmdr1 gene copy numbers associated with anti-malarial drug resistance, from RDT and filter paper extracted DNA collected from 121 RDT positive field samples.