Table 1.
Demographic and clinical characteristics of patients with bacteremic hospital-acquired pneumonia caused by Acinetobacter baumanniia
|
Demographic or characteristic |
Non-ventilator-associated (n = 48) |
Ventilator-associated (n = 96) |
p Value |
|---|---|---|---|
| n (% or IQRa) | |||
| Age in year |
74 (54.8-81.8) |
74 (59.0-80.0) |
0.944 |
| Gender, male |
40 (83.3) |
73 (76.0) |
0.43 |
| Acquired in ICU |
12 (25.0) |
84 (87.5)b |
<0.001 |
| ICU admission after pneumonia |
19 (39.6)c |
86 (89.6) |
<0.001 |
| Days of hospitalization prior to bacteremia |
14.5 (3.2-3.6) |
22.5 (12.0-40.8) |
0.021 |
| Comorbidity |
|
|
|
| Charlson comorbidity score |
3 (2.0-5.0) |
3 (2.0-5.0) |
0.861 |
| Hypertension |
22 (45.8) |
47 (49.0) |
0.86 |
| Coronary artery disease |
14 (29.2) |
15 (15.6) |
0.091 |
| Congestive heart failure |
6 (12.5) |
19 (19.8) |
0.392 |
| Cerebral vascular disease |
7 (14.6) |
27 (28.1) |
0.111 |
| COPD |
12 (25.0) |
27 (28.1) |
0.842 |
| Non-COPD chronic lung disease |
5 (10.4) |
15 (15.6) |
0.551 |
| Alcohol |
3 (6.3) |
13 (13.5) |
0.302 |
| Liver cirrhosis |
4 (8.3) |
5 (5.2) |
0.481 |
| Chronic kidney disease |
15 (31.3) |
32 (33.3) |
0.95 |
| Type 2 diabetes |
10 (20.8) |
35 (36.5) |
0.086 |
| Collagen vascular disease |
4 (8.3) |
7 (7.3) |
1 |
| Usage of immunosuppressants |
18 (37.5) |
32 (33.3) |
0.757 |
| Usage of corticosteroids |
7(14.6) |
23 (24.0) |
0.276 |
| Neutropenia |
4 (8.3) |
7 (7.3) |
1 |
| Malignancy |
22 (45.8) |
28 (29.2) |
0.073 |
| Hematologic malignancy |
7 (14.6) |
6 (6.3) |
0.125 |
| Solid malignancy |
17 (35.4) |
23 (24.0) |
0.211 |
| Previous shock |
8 (16.7) |
27 (28.1) |
0.192 |
| Recent surgery |
8 (16.7) |
34 (35.4) |
0.032 |
| Trauma |
0 (0) |
4 (4.2) |
0.301 |
| Proceduresd |
|
|
|
| Abdominal drain |
1 (2.1) |
5 (5.2) |
0.658 |
| Arterial line |
5 (10.4) |
36 (37.5) |
0.001 |
| Central venous catheter |
22 (45.8) |
71 (74.0) |
0.002 |
| Pulmonary artery catheter |
6 (12.5) |
20 (20.8) |
0.319 |
| Foley catheter |
28 (58.3) |
78 (81.3) |
0.006 |
| Hemodialysis |
4 (8.3) |
10 (10.4) |
0.774 |
| Nasogastric tube |
35 (72.9) |
93 (96.9) |
<0.001 |
| Thoracic drain |
0 (0) |
7 (7.3) |
0.095 |
| Total parental nutrition |
1 (2.1) |
8 (8.3) |
0.273 |
| Tracheostomy |
7 (14.6) |
16 (16.7) |
0.936 |
| Shockd |
29 (60.4) |
58 (60.4) |
1 |
| APACHE II scored |
24 (17.3-31.8) |
27 (21.3-34.8) |
0.015 |
| Radiological features |
|
|
|
| Bilateral radiologic involvement |
27 (56.3) |
81 (84.4) |
0.001 |
| Pleural effusion |
20 (41.7) |
32 (33.3) |
0.425 |
| Appropriate antimicrobial therapy |
20 (41.7) |
28 (29.2) |
0.189 |
| Combination antimicrobial therapy |
4 (8.3) |
7 (7.3) |
1 |
| Outcome |
|
|
|
| 14-day mortality | 21 (43.8) | 30 (31.3) | 0.196 |
aData are median value (interquartile range) for continuous variables and number of cases (%) for categorical variables. IQR = interquartile range; ICU = intensive care unit; COPD = chronic obstructive pulmonary disease; APACHE = Acute Physiologic and Chronic Health Evaluation.
bOther patients were cared in a respiratory care center, respiratory ward, or common ward.
cTwelve acquired pneumonia in an ICU and 7 outside an ICU, all of them received mechanical ventilation after pneumonia.
dAt the time the blood culture was obtained.