Figure 4.

Effects of CPA alone and in combination with L-BLP25 on serum pro-inflammatory cytokines. Serial serum specimens were analyzed for 20 cytokines 24 hours after the 4^th (A) and 8^th (B) doses of L-BLP25, and 24 hours after the CPA 100- and 300-mg/kg doses (C). Blood was pooled within each treatment group (n = 3-6, depending on blood volume obtained). For each treatment group, serum concentrations represent the mean and bars represent the range. Serum concentrations of IP-10, MIG, MIP-1α and MCP-1 were elevated in the CPA + L-BLP25 group compared to vaccine alone.