Figure 5. Functional changes in NK cells from lung transplant patients.

PBMC from ten LTR, not receiving immunosuppression pre-transplant (Pre-Tx), were stimulated in culture with PMA-I. Individual graphs of NK cell CD107a expression (closed square) and IFN-γ production (open circle) from LTR with clinically stable post-transplantation follow-up (Tx #6, #7, #9), episodes of acute rejection (Tx #2, #3, #4) or viral infection (Tx #1, #5, #8, #10). The arrows represent the occurrence of each clinical event in the months post-transplant.