Figure 2. Cancer growth susceptibility and resistance of SR/CR mice and nonresistant controls.
The SR/CR mice resisted the s.c. injection of S180 cells, whereas the C57BL/6 mice developed tumors 8–30 days after s.c. injection of S180 cells which was at a significantly higher frequency (p<0.0001). SR/CR and C57BL/6 mice both developed tumors 8–14 days after the transplantation or s.c. injection of EL4 cells. SR/CR mice were inoculated i.p. with 8×105 J774A.1 cells and ascites developed 34–40 days later, and this resistance was significantly lower (p<0.0081) compared to the resistance of SR/CR mice to S180 cells.