Table 1. Clinical data of the study cohort.
Characteristics | Controls | Chronic Liver Disease Patients | Patients with MRI and Morphometry |
N | 10 | 65 | 59 |
Gender (female/male) | 3/7 | 31/34 | 29/30 |
Age (years), median (range) | 33.5 (24–47) | 56 (20–72)* | 56 (20–72)* |
BMI (kg/m2), mean ± st. dev. | 22.55±1.77 | 29.00±5.11# | 28.92±5.17# |
LIC (mg/g), median (range) | 1.2 (0.4–1.8) | 0.9 (0.3–4.8) | 0.9 (0.3–4.4) |
Diagnosis | |||
AIH | 3 | 3 | |
ALD | 3 | 2 | |
HBV-HCV | 18 | 16 | |
NAFLD | 11 | 10 | |
NASH | 19 | 17 | |
NORM | 3 | 3 | |
PSC | 4 | 4 | |
OTHER | 4 | 4 |
Significantly different from controls, p<0.05 Mann-Whitney test.
Significantly different from controls, p<0.05 unpaired t-test. Abbreviations: AIH, autoimmune hepatitis; ALD, alcoholic liver disease; BMI, body mass index; HBV-HCV, chronic viral hepatitis B/C; LIC, liver iron concentration; MRI, magnetic resonance imaging; NAFLD, non-alcoholic fatty liver disease – simple steatosis; NASH, nonalcoholic steatohepatitis; NORM, normal; PSC, primary sclerosing cholangitis.