Table 2. Analysis of the area under the receiver operating characteristic curve using the histopathologist’s visual estimate of fat in the histological sections.
Cut-off | MRI Cut off Value (α) | AUC | p value | Sensitivity | 95% CI | Specificity | 95% CI |
≥5% (Grade 0 vs 1–3)* | >0.067 | 0.9615 | <0.0001 | 90.91 | 75.67 to 98.08 | 96.15 | 80.36 to 99.90 |
>33% (Grade 0–1 vs 2–3)* | >0.135 | 0.9928 | <0.0001 | 100.0 | 85.18 to 100.0 | 97.22 | 85.47 to 99.93 |
>66% (Grade 0–2 vs 3)* | >0.171 | 0.9724 | <0.0001 | 100.0 | 79.41 to 100.0 | 88.37 | 74.92 to 96.11 |
Cut-offs are defined according to the NASH CRN grading system. Abbreviations: AUC, Area under receiver operating characteristic curve; CI, confidence interval; MRI, magnetic resonance imaging.