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. 2013 Mar 21;8(3):e59287. doi: 10.1371/journal.pone.0059287

Table 2. Analysis of the area under the receiver operating characteristic curve using the histopathologist’s visual estimate of fat in the histological sections.

Cut-off MRI Cut off Value (α) AUC p value Sensitivity 95% CI Specificity 95% CI
≥5% (Grade 0 vs 1–3)* >0.067 0.9615 <0.0001 90.91 75.67 to 98.08 96.15 80.36 to 99.90
>33% (Grade 0–1 vs 2–3)* >0.135 0.9928 <0.0001 100.0 85.18 to 100.0 97.22 85.47 to 99.93
>66% (Grade 0–2 vs 3)* >0.171 0.9724 <0.0001 100.0 79.41 to 100.0 88.37 74.92 to 96.11
*

Cut-offs are defined according to the NASH CRN grading system. Abbreviations: AUC, Area under receiver operating characteristic curve; CI, confidence interval; MRI, magnetic resonance imaging.