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. 2013 Mar 21;8(3):e59250. doi: 10.1371/journal.pone.0059250

Figure 5. Runx1 is expressed by a subpopulation of putative neural stem cells in the subventricular zone.

Figure 5

Runx1 (red) was co-expressed with Nestin (green) in cells of the lateral and apical subventricular zone after injury, between 3 dpi (A, inset a, a′, a′′) and 30 dpi (C, inset c, c′, c′′). Some of these cells also expressed GFAP (B, inset b, b′, b′′). Runx1 was not expressed by DCX+ (D, green) or Mash1+ (E, green) cells after injury, but was often immediately adjacent to clusters of DCX+ cells (D). Scale bars for B, a′′, b′′, c′′ = 20 µm; for A, C, D, and E = 50 µm. Abbreviations: subventricular zone (SVZ), lateral ventricle (LV), days post-injury (dpi).