TABLE 5.
GO categories of mRNAs significantly up- or down-regulated by loss of Mio/dChREBP in the fat body
COPI, coatomer protein 1.
| GO category | p value | Genes | Up- or down-regulated |
|---|---|---|---|
| Ribosome | 1.18 × 10−45 | cg6764, mrpl10, mrpl17, mrpl21, mrpl23, mrpl24, mrpl27, mrpl30, mrpl36, mrpl39, mrpl40, mrpl41, mrpl46, mrpl51, mrpl52, mrps5, mrps14, mrps16, mrps17, mrps18c, mrps22, mrps25, mrps26, mrps28, qm, rpl7a, rpl8, rpl9, rpl11, rpl12, rpl13a, rpl19, rpl21, rpl23, rpl29, rpl30, rpl36, rpl38, rpl39, rplp1, rplp2, rps3, rps5a, rps6, rps9, rps10b, rps11, rps14a, rps14b, rps15aa, rps15ab, rps17, rps18, rps23, rps27a, rps29, tko | Up |
| Mitochondrion | 1.07 × 10−35 | aldh, arg, cchl, cg1824, cg1907, cg2543, cg2658, cg2789, cg3621, cg3683, cg3719, cg3803, cg4095, cg4225, cg4592, cg4598, cg4769, cg4995, cg5037, cg5254, cg5548, cg6020, cg6404, cg6412, cg6439, cg7430, cg7598, cg7943, cg8680, cg8728, cg9172, cg9547, cg10320, cg12400, cg14482, cg31075, cg32230, cg32250, cg32649, cova, cyp12a4, dnapol-γ35, eftum, ferrochelatase, gata, got2, hsp60, hsp68, idh, l(1)g0255, l(2)37cc, mrpl10, mrpl17, mrpl21, mrpl23, mrpl24, mrpl27, mrpl30, mrpl36, mrpl39, mrpl40, mrpl41, mrpl46, mrpl51, mrpl52, mrps5, mrps14, mrps16, mrps17, mrps18c, mrps22, mrps25 mrps26, mrps28, mtacp1, mt:coi, mt:coii, mt:coiii, mt:cyt-b, mt:nd1, mt:nd2, mt:nd3, mt:nd4l, mt:nd5, mt:nd6, nd75, nemy, oat, pink1, porin, scpx, scsα, scu, sucb, sun, surf1, t-cp1, tko, yip2 | Up |
| COPI vesicle coat | 2.24 × 10−6 | chop24, αcop,β cop, γcop,ε cop,δ cop, ζcop | Up |
| Electron transport | 1.30 × 10−10 | cg3560, cg3621, cg3683, cg4169, cg4769, cg5548, cg6020, cg6666, cg7181, cg8680, cg9172, cg10320, cg11015, cg11455, cg12079, cg12859, cg14482, cg12400, cg17280, cg32230, cg32649, cg41623, cova, cyt-b5, mtacp1, mt:coi, mt:coii, pdsw, rfesp, ox | Up |
| Proteolysis | 6.91 × 10−8 | aos1, ate1, cg2200, cg7142, cg8299, cg8952, cg9631, cg10472, cg10908, cg11911, cg11912, cg12000, cg13779, cg16749, cg16996, cg16997, cg17571, cg17684, cg18179, cg18180, cg30025, cg30031, cg31728, cg32147, ice, jon66ci, pros45, jon25biii, jon25bii, jon25bi, jon44e, jon65ai, jon65aii, jon65aiii, jon65aiv, jon66cii,jon74e, jon99ci, jon99cii, jon99ciii, jon99fii, kaz1-orfb, roc1a, αtry,β try,δ try,ε try, ηtry, ιtry, θtry, pros26.4, pros28.1, pros29, pros35, prosma5, psn, rpn7, rpn11, rpn12, rps27a, rpt3, sras, ter94, th, uch-l3, w, yip7 | Up |
| Growth regulation | 1.58 × 10−5 | akt1, babo, chico, dsx, eif-4e, foxo, lack, lk6, path, phl, pi3k92e, pk61c, s6k, samuel,β -spec, thor, tkv, tor, tsc1, tsg101, wts, yki | Down |
| Protein transport | 1.64 × 10−5 | arr, cact, cas, cg4289, cg6359, cg6842, cg9426, cg14804, cora, cos, dco, emb, fbp1, fs(2)ket, hkl, hop, kap-α1, kap-α3, lwr, mbo, nup214, olf186-f, sec6, slmb, srp54k, srprβ, tim8, tom40, tom70 | Down |
| Programmed cell death | 4.66 × 10−5 | aac11, ago2, akap200, akt1, ark, art4, bruce, cas, cbt, cg3829, cg5651, cg17019, decay, dream, ecr, egfr, egr, eif-4e, eip74ef, eip75b, hkl, hr78, ik2, l(1)g0148, l(2)01424, ofs, pall, pk61c, pnt, pp2a-b′, pr2, puc, raw, sktl, slmb, usp, wts, yki, zip | Down |
| Immune system process | 8.17 × 10−6 | adgf-a, ago2, brm, cact, cdc42, cg6509, dcr-2, dif, egfr, egr, eip75b, gef26, hel89b, hep, hop, kis, lola, lwr, mask, mbo, mp1, mys, nej, par-1, pgrp-lc, pgrp-le, phl, pnt, pvr, r, rac1, rel, rho1, srp, stat92e, su(var)2–10, tab2, tepii, thor, tl, tlk, tub, ush, ytr | Down |
| Hemocyte differentiation | 8.65 × 10−6 | adgf-a, dif, egfr, hep, hop, lwr, phl, pnt, pvr, rac1, srp, stat92e, tl, ush, ytr | Down |
| Histone modification | 7.51 × 10−6 | art4, ash1, atac1, bur, cg1716, cg10542, cg15835, e(z), jil-1, parg, pr-set7, rpd3, rtf1, sir2, su(var)4–20, su(z)12, tlk | Down |