FIGURE 3.

The CAG repeat number in the AR gene is stable during reprogramming and differentiation. GeneScan analyses indicating that fibroblasts have 47 and 49 CAG repeats in the AR gene are shown. Both KAS01 #2 and #3 iPSCs had only 47 repeats, even after long term passage. Differentiation (differentiated neurons and teratomas) does not influence the number of CAG repeats. DRP01 #7, which contains the normal 20 CAG repeats in the AR gene, was used as a control iPSC line. P indicates passage number.