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. 2013 Jan 18;288(12):8365–8379. doi: 10.1074/jbc.M112.442905

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© 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 1. — Impact of Grx2^−/− on whole body energetics and mouse physiology. a, mouse weight. Student's t test, n = 4, mean ± S.E. b, effect of Grx2^−/− on tissue and organ weights. Student's t test, n = 4, mean ± S.E. BAT, interscapular brown adipose tissue; GWAT, gonadal white adipose tissue. c, hematoxylin and eosin staining of gastrocnemius (×40 objective) and liver (×20 objective) cross-sections. d, measurement of whole body energetics by indirect calorimetry. n = 6. e, impact of Grx2^−/− on respiratory exchange ratio (RER) and mouse activity in WT and Grx2^−/− mice during light and dark phases. Student's t test, n = 6, mean ± S.E. f, daily food intake. Measurements were taken every 3–4 days and corrected for spillage. n = 5, mean ± S.E.