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Edelfosine does not induce internalization of the MCC resident protein Sur7p. a, cells with endogenously expressed Pma1p-RFP (top panel) or Sur7p-GFP (bottom panel) were grown to log phase in the absence (control) or presence of edelfosine (19 μm) for 1 h at 30 °C. Arrows indicate changes in the distribution pattern of Sur7p after treatment with edelfosine. b, quantitation of at least 100 cells from each condition. IC, intracellular; EDLF, edelfosine.
