FIGURE 2.
Mapping of the dimerization domain of progranulin. A, a schematic representation of deletion mutants of mouse progranulin is shown. B, mapping of dimerization domain of progranulin in co-immunoprecipitation (IP) assays is shown. Conditioned media from transfected HEK293T cells was subjected to immunoprecipitation with anti-FLAG magnetic beads. Similar results were obtained in three independent experiments.