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. 2013 Jan 30;288(12):8627–8635. doi: 10.1074/jbc.M112.441949

FIGURE 2.

FIGURE 2.

Mapping of the dimerization domain of progranulin. A, a schematic representation of deletion mutants of mouse progranulin is shown. B, mapping of dimerization domain of progranulin in co-immunoprecipitation (IP) assays is shown. Conditioned media from transfected HEK293T cells was subjected to immunoprecipitation with anti-FLAG magnetic beads. Similar results were obtained in three independent experiments.