Table 3.
Model results of the association of ADHD symptoms score with treatment, nicotine withdrawal symptoms, craving to smoke and abstinence status after target quit date (weeks 2, 4 and 6 post-quit).
Basic modela |
Basic model plus withdrawal |
Basic model plus interaction OROS-MPH (vs.placebo) and withdrawal |
Basic model plus craving |
Basic model plus interaction OROS-MPH (vs.placebo) and craving |
|
---|---|---|---|---|---|
β (s.e.) | |||||
Abstinence | 0.28 (0.72) |
0.41 (0.71) |
0.42 (0.71) |
0.14 (0.76) |
0.13 (0.76) |
OROS-MPH (vs. placebo) |
−6.05 ** (1.38) |
−4.50 * (1.26) |
−7.36 ** (1.65) |
−5.98 ** (1.36) |
−5.40* (1.76) |
Withdrawal symptoms | 0.55 ** (0.07) |
0.38 ** (0.09) |
|||
Interaction between OROS-MPH (vs. placebo) and withdrawal |
0.35 * (0.13) |
||||
Craving | 0.35 (0.30) |
0.50 (0.41) |
|||
Interaction between OROS-MPH (vs. placebo) and craving |
−0.30 (0.58) |
p<0.001,
p<0.0001
Adjusted for age, gender, race, treatment, week of assessment, site, nicotine patch compliance, osmotic-release oral system methylphenidate (OROS-MPH) vs. placebo compliance, and baseline ADHD score.
ADHD: attention-deficit/hyperactivity disorder