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. Author manuscript; available in PMC: 2013 Mar 22.
Published in final edited form as: Soft Matter. 2011 Apr 7;7(7):3373–3382. doi: 10.1039/C0SM01192D

Table 2.

Relative contributions of different amino acid sidechains to the interprotein attractions. Hyp is hydroxyproline; all other residues are standard. Amino acids are listed in the order of the number of times they appear in a collagen protein, n, and charged amino acids are indicated in parentheses. The data are presented so that each column sums to 100%

hydrogen bond hydrogen bond water bridge water bridge
sidechain n donor acceptor donor acceptor
Hyp 328 11.2% 7.0% 21.2% 11.1%
Arg (+) 158 47.6% 0.0% 39.7% 0.0%
Glu (−) 145 0.0% 54.1% 0.0% 45.6%
Ser 131 12.2% 3.5% 8.5% 4.9%
Lys (+) 110 15.9% 0.0% 14.1% 0.0%
Asp (−) 90 0.0% 26.7% 0.0% 23.5%
Gln 83 5.9% 5.8% 8.0% 8.9%
Thr 64 3.1% 0.7% 3.3% 2.5%
Asn 48 1.8% 1.5% 4.1% 2.4%
Tyr 14 1.1% 0.5% 0.4% 0.8%
His 13 1.1% 0.2% 0.7% 0.4%