Skip to main content
. 2012 Dec 10;4(3):418–434. doi: 10.1021/cn3001334

Table 2. Comparison of Analogous Peptides Localized within the AVK in A. suum, C. elegans, and G. pallidaa.

A. suum
C. elegans
G. pallida
gene peptide sequence AVK gene peptide sequence AVK gene peptide sequence AVK
afp-11 KPNFIRFab yes flp-1 SADPNFLRFab yes gpflp-4 SDPNFLRFa no
  TAPPLTFa     SQPNFLRFab     TSSNFLRFa  
  (TAPPLTFGKK)GSDPNFLRFac     ASGDPNFLRFab     SSASMSTSSEPNFLRFa  
  GSDPNFLRFa     SDPNFLRFab     GGVDPTFLRFa  
  TPSNNFLRFab     AAADPNFLRFab     ANNNFLRFa  
  SNQAQNFLRFab     (K)PNFLRFa     QANPNFLRFa  
  NAEPNFLRFab     AGSDPNFLRFa        
  PADPNFLRFab     (K)PNFMRYa        
  SAEPNFLRFab              
  SD(I/V)GISEPNFLRFad,e              
  NNFLRFab              
  NDQFDREYb              
  (NDQFDREYR)KPNFLRFac              
  KPNFLRFab              
                 
afp-4 KHEYLRFab yes flp-14 KHEYLRFa NA gpflp-3 KHEYLRFa no
a

In A. suum, afp-11 was localized by MALDI-TOF MS and in situ hybridization. afp-4 has been localized in AVK by MALDI-TOF MS. In C. elegans, flp-1 was localized using GFP constructs.13,35 In G. pallida, in situ hybridization did not detect gpflp-1 and gpflp-14 in AVK.12

b

Peptides isolated and sequenced.

c

Incompletely processed peptide.

d

Located in AVK by immunocytochemistry.

e

Both I and V forms have been detected.