Table 2. Comparison of Analogous Peptides Localized within the AVK in A. suum, C. elegans, and G. pallidaa.
A. suum |
C. elegans |
G. pallida |
||||||
---|---|---|---|---|---|---|---|---|
gene | peptide sequence | AVK | gene | peptide sequence | AVK | gene | peptide sequence | AVK |
afp-11 | KPNFIRFab | yes | flp-1 | SADPNFLRFab | yes | gpflp-4 | SDPNFLRFa | no |
TAPPLTFa | SQPNFLRFab | TSSNFLRFa | ||||||
(TAPPLTFGKK)GSDPNFLRFac | ASGDPNFLRFab | SSASMSTSSEPNFLRFa | ||||||
GSDPNFLRFa | SDPNFLRFab | GGVDPTFLRFa | ||||||
TPSNNFLRFab | AAADPNFLRFab | ANNNFLRFa | ||||||
SNQAQNFLRFab | (K)PNFLRFa | QANPNFLRFa | ||||||
NAEPNFLRFab | AGSDPNFLRFa | |||||||
PADPNFLRFab | (K)PNFMRYa | |||||||
SAEPNFLRFab | ||||||||
SD(I/V)GISEPNFLRFad,e | ||||||||
NNFLRFab | ||||||||
NDQFDREYb | ||||||||
(NDQFDREYR)KPNFLRFac | ||||||||
KPNFLRFab | ||||||||
afp-4 | KHEYLRFab | yes | flp-14 | KHEYLRFa | NA | gpflp-3 | KHEYLRFa | no |
In A. suum, afp-11 was localized by MALDI-TOF MS and in situ hybridization. afp-4 has been localized in AVK by MALDI-TOF MS. In C. elegans, flp-1 was localized using GFP constructs.13,35 In G. pallida, in situ hybridization did not detect gpflp-1 and gpflp-14 in AVK.12
Peptides isolated and sequenced.
Incompletely processed peptide.
Located in AVK by immunocytochemistry.
Both I and V forms have been detected.