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In vitro profile of AZD1981 across species
| Species | [3H]PGD2 binding | AZD1981 |
|---|---|---|
| pKd | pIC50 | |
| Human | 8.3 ± 0.1 (n = 4a | 8.4 ± 0.1 (n = 25) |
| Rat | 8.3 ± 0.0 (n = 2a | 8.5 ± 0.1 (n = 4) |
| Mouse | 8.1 ± 0.2 (n = 2a | 8.1 ± 0.2 (n = 4) |
| Dog | 8.2 ± 0.1 (n = 3a | 8.1 ± 0.2 (n = 4) |
| Guinea pig | 8.3 ± 0.4 (n = 2a | 7.8 ± 0.2 (n = 6) |
| Rabbit | 8.0 ± 0.1 (n = 3) | 8.7 ± 0.1 (n = 8) |
Data from Carrillo et al. (2005).
