Table 3.

[¹²⁵I]-CXCL12 dissociation half-life from CXCR4 is decreased in the presence of CXCR3

	t1/2 ± SEM (min)
	CXCR4	CXCR3 + CXCR4
Buffer	93 ± 15	56 ± 8
100 nM CXCL10	81 ± 9	32 ± 8#
100 nM CXCL12	12 ± 1*	24 ± 6*
100 nM VUF10661	83 ± 25	16 ± 3*

Results shown are average ± SEM of three or more independent experiments performed in triplicate.

^*t_1/2 differs significantly from t_1/2 in presence of vehicle (P < 0.05).

^#t_1/2 differs significantly from t_1/2 in membranes expressing CXCR4 alone (P < 0.05).