Table 3.
Association of noncalcified coronary plaque with serologic findings and treatment from the same day (current) visit in our study group (n = 147). Data were missing for some variables.
| Factor | Mean Noncalcified Plaque Score (SD) | p | Differences Between Subgroups in Mean Plaque Score Controlling for Age (95% CI) | p Controlling for Age |
|---|---|---|---|---|
| C3 < 79 mg/dl | ||||
| No, n = 114 | 0.23 (0.30) | 0.90 | Reference group | 0.53 |
| Yes, n = 25 | 0.22 (0.27) | 0.04 (−0.08, 0.16) | ||
| C4 < 2 mg/dl | ||||
| No, n = 119 | 0.24 (0.30) | 0.85 | Reference group | 0.32 |
| Yes, n = 20 | 0.23 (0.29) | 0.07 (−0.07, 0.20) | ||
| Lupus anticoagulant (dRVVT) | ||||
| No, n = 107 | 0.23 (0.30) | 0.59 | Reference group | 0.62 |
| Yes, n = 23 | 0.26 (0.30) | 0.03 (−0.10, 0.16) | ||
| Anticardiolipin IgG > 20 | ||||
| No, n = 126 | 0.22 (0.29) | Reference group | ||
| Yes, n = 9 | 0.42 (0.37) | 0.046 | 0.22 (0.03, 0.41) | 0.026 |
| Current anti-dsDNA | ||||
| No, n = 109 | 0.25 | 0.20 | Reference group | 0.80 |
| Yes, n = 27 | 0.17 | −0.02 (−0.14, 0.11) | ||
| Corticosteroids | ||||
| No, n = 98 | 0.25 (0.30) | 0.29 | Reference group | 0.66 |
| Yes, n = 48 | 0.20 (0.27) | −0.02 (−0.12, 0.08) | ||
| Hydroxychloroquine | ||||
| No, n = 24 | 0.22 (0.23) | 0.79 | Reference group | 0.99 |
| Yes, n = 122 | 0.24 (0.30) | 0.00 (−0.12, 0.12) | ||
| Azathioprine | ||||
| No, n = 134 | 0.24 (0.30) | 0.53 | Reference group | 0.61 |
| Yes, n = 13 | 0.18 (0.19) | −0.04 (−0.20, 0.12) | ||
| Methotrexate | ||||
| No, n = 138 | 0.21 (0.26) | 0.0001 | Reference group | 0.0001 |
| Yes, n = 9 | 0.59 (0.50) | 0.38 (0.19, 0.56) | ||
| Mycophenolate mofetil | ||||
| No, n = 128 | 0.25 | 0.097 | Reference group | 0.52 |
| Yes, n = 19 | 0.13 | −0.04 (−0.18, 0.09) | ||
| NSAID | ||||
| No, n = 91 | 0.25 | 0.45 | Reference group | 0.37 |
| Yes, n = 55 | 0.21 | −0.04 (−0.13, 0.05) | ||
| Physical global assessment | ||||
| < 0.5 | 0.19 | 0.37 | Reference group | 0.27 |
| 0.5–0.99 | 0.27 | 0.08 (−0.02, 0.19) | ||
| 1+ | 0.24 | 0.07 (−0.06, 0.19) | ||
| Current SLEDAI | ||||
| 0–2 | 0.23 | 0.71 | Reference group | 0.34 |
| 3+ | 0.25 | 0.05 (−0.05, −0.15) | ||
dRVVT: dilute Russell’s viper venom test; NSAID: nonsteroidal antiinflammatory drugs; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index.