Table 2.
Sensitivity and Target Size
| Vendor | Designed bait region size | Percent of 3.5-Mb targeted region | % Reads mapping to baits | % Bait region covered >1× | % Bait region covered >10× |
|---|---|---|---|---|---|
| Agilent | 1,635,961 | 46.5% | 69.9% | 99.7% | 98.0% |
| NimbleGen microarray | 2,827,999 | 80.4% | 81.4% | 99.9% | 99.7% |
| NimbleGen SeqCap | 2,827,999 | 80.4% | 82.7% | 99.9% | 99.6% |
Each vendor generated a bait design with the goal of capturing the majority of the 3.5-Mb targeted region. Agilent's bait design covered only 1.6 Mb, whereas NimbleGen's covered 2.8 Mb. Each platform had high mapping and coverage rates to their bait regions.