Table I.

Laboratory findings in healthy control dogs and dogs with chronic kidney disease (CKD)^a

	Mean and standard deviation
Measure	Control	CKD	P-value
Hematocrit (%)	48.27 ± 2.9b	31.26 ± 13.93c	< 0.0004**
Leukocyte count (× 103/μL)	13 ± 3.37b	21.05 ± 11.51c	< 0.0203**
Urine specific gravity	1.044 ± 0.018b	1.016 ± 0.002c	< 0.0105**
Plasma concentration
Albumin (g/L)	30.36 ± 3.29b	25.73 ± 3.7c	< 0.0033*
Cholesterol (mg/dL)	208.0 ± 76.74b	299 ± 121.78c	< 0.0415*
Creatinine (mg/dL)	1.07 ± 0.13b	4.55 ± 3.02c	< 0.0001**
Urea (mg/dL)	46.45 ± 9.85b	315.21 ± 159.95c	< 0.0001**
Uric acid (mg/dL)	1.33 ± 0.59b	1.05 ± 0.82b	< 0.3589*
TBARS (nmol/mL)	43.4 ± 8.39b	21.51 ± 9.39c	< 0.0001*
Plasma TAC (mmol/L)	2.73 ± 0.24b	2.08 ± 0.43c	< 0.0002**

^aNoncoincident letters in the same row represent significant differences in the unpaired t-test (^*) and the unpaired t-test with Welch’s correction (^**).

TBARS — thiobarbituric acid reactive substances, representing plasma lipid peroxidation; TAC — total antioxidant capacity.