Fig. 7.

Cellular incorporation of EPA and DHA dose-dependently decreases arachidonic acid (C20:4n-6). Total lipids were extracted from PBMC after 24 h incubation with increasing concentrations of EPA or DHA, and fatty acid profiles were determined by gas chromatographic analysis. (A) Data are expressed as means ± SEM relating to 100% detectable fatty acids (as FAME). (B) Partial GC chromatograms of PBMC treated either with EPA (upper chart) or DHA (lower chart) in increasing concentrations. n.d., not detected.