TABLE 1.
Cross | Year (Reference) | Number (Sex) | Directa | Age (Weeks) | Notes on Diet |
(NZB×SM)NZB | 2002 (40) | 90 (F) | Uni | 8, 12, 16, 26 | Chow diet first 8 weeks, followed by atherogenic diet for 18 weeks |
D2×CAST | 2003 (41) | 278 (M) | Bi | 16 | Chow diet first 8 weeks, followed by atherogenic diet for 8 weeks |
B6×CASA | 2003 (15) | 184 (F) 185 (M) | Uni | 11 | Chow diet |
B6×D2 | 2003 (16) | 111 (F) | Uni | 52, 68 | Chow diet first 52 weeks, followed by atherogenic diet for 16 weeks |
(B6×NZB)B6 | 2003 (42) | 100 (F) | Uni | 8, 12, 23 | Chow diet first 8 weeks, followed by atherogenic diet for 15 weeks |
SM×NZB | 2004 (43) | 259 (F) 254 (M) | Uni | 8, 14, 20, 24 | Chow diet first 8 weeks, followed by atherogenic diet for 16 weeks |
B6×129S1 | 2004 (44) | 294 (F) | Uni | 20 | Chow diet first 6 weeks, followed by atherogenic diet for 14 weeks |
129S1×CAST | 2004 (45) | 277 (M) | Bi | 16 | Chow diet first 8 weeks, followed by atherogenic diet for 8 weeks |
RIII×129S1 | 2004 (46) | 150 (M) 180 (M) | Bi | 16 20 | Chow diet first 8 weeks, followed by atherogenic diet for 8 or 12 weeks |
PERA×I | 2006 (47) | 164 (F) 141 (M) | Bi | 16 | Chow diet first 8 weeks, followed by atherogenic diet for 8 weeks |
D2×PERA | 2006 (47) | 166 (M) 158 (M) | Bi | 16 | Chow diet first 8 weeks, followed by atherogenic diet for 8 weeks |
B6×A | 2006 (48) | 343 (M) | Uni | 10 | Chow diet |
B6×A | 2006 (48) | 271 (F) | Uni | 8 | Chow diet |
NZB×RF | 2007 (49) | 542 (F) | Uni | 10 | Chow diet |
D2×DU6i | 2007 (50) | 228 (M) 174 (F) | Uni | 6 | Chow diet |
B6.Apoe−/−×C3H.Apoe−/− | 2008 (51) | 241(F) | Uni | 18 | Chow diet first 6 weeks, followed by western diet for 12 weeks |
B6×C3H | 2009 (52) | 277 (F) | Uni | 14 | Chow diet first 8 weeks, followed by atherogenic diet for 6 weeks |
(NZO×NON)NON | 2009 (52) | 204 (M) | Bi | 24 | Chow diet |
B6×D2 | 2009 (52) | 340 (M) | Uni | 8 | Chow diet |
B6×129S1 | 2009 (19) | 242 (F) 249 (M) | Uni | 11, 18 | Chow diet first 11 weeks, followed by atherogenic diet for 7 weeks |
NOD(NOD×129.H2g7) | 2009 (53) | 159 (F) | Uni | 40 | Chow diet |
B6×NOD | Unpublished | 139 (M) | Uni | 10 | Chow diet |
B6×NZW | Unpublished | 143 (M) | Uni | 10 | Chow diet |
Uni = all F1 animals were produced using the direction as indicated in the first column, with the first strain being the female; bi = F1 animals were produced using both directions.