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. Author manuscript; available in PMC: 2013 Mar 22.
Published in final edited form as: Transfusion. 2010 Dec 23;51(6):1197–1206. doi: 10.1111/j.1537-2995.2010.02991.x

TABLE 3B.

Estimated number of apheresis PLT donations lost based on the deferral of ever-pregnant female donors with positive screening tests for HLA antibodies

Donation characteristic Number of apheresis PLTs donations from female donors* Percentage of total donations from donors of both sexes Proportion of female donors who could potentially have HLA antibodies Number of apheresis PLT donations from female donors with HLA antibodies Percentage of total donations from donors of both sexes
Number of pregnancies
 None 31,855 11.3 NA NA
 One 11,373 4.0 0.112 1,274 0.5
 Two 21,943 7.8 0.223 4,893 1.7
 Three 15,616 5.5 0.275 4,294 1.5
 Four or more 14,719 5.2 0.322 4,740 1.7
Pregnancy history information
 Donations from female donors without information on pregnancy history 9,227 3.3
 Donations from never-pregnant donors 31,855 11.3
 Donations from ever-pregnant donors 63,651 22.5 15,201 5.4
Total number of donations
 Donations from female donors 104,733 37.1
 Donations from male donors 177,567 62.9
 Donations from female and male donors§ 282,300 100.0 282,300 100.0
*

This number includes donations of apheresis PLTs with or without concurrent RBC and/or plasma.

Column percentages.

Based on the REDS-II LAPS-I study and assuming that never-pregnant donors will not have any HLA antibodies.

§

From Table 1.