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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2012 Mar 5;520(2):108–116. doi: 10.1016/j.abb.2012.02.018

Fig. 2.

Fig. 2

Spectra of ligand-free and DAR-bound WT and R212A CYP3A4. Absorbance spectra of 1.2 μM CYP3A4 were recorded in the absence and presence of 6 μM DAR. Insets a and b, plots of absorbance changes observed during equilibrium titrations of WT and R212A CYP3A4, respectively, vs. DAR concentration. Ks values derived from the plots are given in Table 2.