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. Author manuscript; available in PMC: 2013 Apr 15.
Published in final edited form as: Arch Biochem Biophys. 2012 Mar 5;520(2):108–116. doi: 10.1016/j.abb.2012.02.018

Fig. 7.

Fig. 7

Inhibitory potency of ritonavir (A) and DTMCR (B) on the BFC hydroxylase activity of CYP3A4. Experiments were conducted as described in the ‘‘Materials and methods’’ section. Concentrations required for half-maximal CYP3A4 inactivation (IC50) are indicated.