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. Author manuscript; available in PMC: 2013 Oct 5.
Published in final edited form as: J Chromatogr A. 2012 Aug 17;1258:76–83. doi: 10.1016/j.chroma.2012.08.036

Fig. 6.

Fig. 6

Effect of porous shell thickness and solute molecular weight on column efficiency. Columns: 4.6 mm × 150 mm; particles: 4 μm; instrument: Agilent 1100 with autosampler. 1-Cl-4-nitrobenzene (MW = 158) – Conditions as in Fig. 2; capacity factors k of 1-chloro-4-nitrobenzene = 2.7, 1.2 for 0.6 and 0.2 μm shell thickness, respectively. Verapamil (MW = 491) – Mobile phase: 30% acetonitrile/70% 0.1% aqueous trifluoroacetic acid; temperature: 40 °C; injection: 0.5 μL; capacity factors k of verapamil = 7.3, 3.6 for 0.6 and 0.2 μm shell thickness, respectively.