Overall structure. (a) Overall fold shown as a cartoon diagram in two orientations related by a 90° rotation about a vertical axis. YopH is shown in salmon and SycH in purple. (b) Topology of the polypeptide chains. (c) Secondary-structure alignment with the polypeptide sequence. Key: blue H, helices; red β, strands; magenta β, β-turn; magenta γ, γ-turn; red loop, β-hairpin. (b) and (c) were generated by PDBSum (Laskowski, 2009 ▶).