Table 1.
Demographic and clinical characteristics of HIV-infected participants.
| Characteristic | Overall, n=116 | Elevated PASP n=18 | Elevated TRV n=9 |
|---|---|---|---|
|
| |||
| Age, mean years (SD) | 47.7 (9.3) | 50.8 (4.1) | 46.8 (4.1) |
|
| |||
| Male, n (%) | 81 (69.8) | 11 (61.1) | 5 (55.6) |
|
| |||
| Race/ethnicity, n (%) | |||
| White | 60 (51.7) | 9 (50.0) | 3 (33.3) |
| African-American | 51 (44.0) | 9 (50.0) | 6 (66.6) |
| Hispanic | 5 (4.3) | 0 | 0 |
|
| |||
| HIV risk factor, n (%) | |||
| MSM | 54 (46.6) | 8 (44.4) | 4 (44.4) |
| Heterosexual | 38 (32.8) | 4 (22.2) | 3 (33.3) |
| Other or unknown | 24 (20.7) | 6 (33.3) | 2 (22.2) |
|
| |||
| Hepatitis ever, n (%) | 15 (13.0) | 2 (11.1) | 1 (11.1) |
|
| |||
| ART use, n (%) | 103 (88.8) | 15 (83.3) | 7 (77.8) |
|
| |||
| Ever smoker, n (%) | 95 (81.9) | 14 (77.8) | 45 (86.5) |
|
| |||
| Current smoker, n (%) | 64 (55.2) | 11 (61.1) | 7 (77.8) |
|
| |||
| IDU in past 6 months, n (%) | 1 (0.86) | 0 | 0 |
|
| |||
| CD4 cell count, median cells/μl, (range) | 578 (24–1798) | 644 (24–1493) | 606 (24–1213) |
|
| |||
| CD4 cell count below 200 cells/μl, n (%) | 9 (7.8) | 3 (16.7) | 3 (33.3)* |
|
| |||
| Mean log10 HIV viral level, (SD) | 2.18 (1.04) | 2.55 (1.36) | 3.15 (0.95)* |
|
| |||
| Detectable HIV viral level, n (%) | 32 (27.6) | 6 (33.3) | 5 (55.6) |
Abbreviations: ART, antiretroviral therapy; IDU, intravenous drug use; MSM, men who have sex with men; PASP, pulmonary artery systolic pressure; SD, standard deviation; TRV, tricuspid regurgitant velocity. Abnormal PASP defined as at least 40 mm Hg and abnormal TRV defined as at least 3.0m/sec. Detectable HIV viral level defined as less than 50 copies/ml.
*
p=0.022 for comparison of CD4 cell count below 200 cells/μl in elevated and normal TRV; p=0.0032 for comparison of log10 HIV RNA level in elevated and normal TRV.