Table 2. Ability of LAMARC to recover θ-values from panel data with sequencing error.
% LAMARC runs rejecting simulation Θ-value |
||||||
---|---|---|---|---|---|---|
Θ | Panel correction | 2 panels | 4 panels | 8 panels | 16 panels | 32 panels |
0.100 | No | 75.8 | 47.0 | 25.0 | 9.0 | 4.0 |
Yes | 7.1 | 7.0 | 3.0 | 3.0 | 1.0 | |
0.010 | No | 74.0 | 53.0 | 35.0 | ||
Yes | 8.0 | 11.0 | 7.0 | |||
0.001 | No | 79.0 | 64.0 | 50.0 | ||
Yes | 8.0 | 8.0 | 8.0 |
Percentage of LAMARC runs rejecting their generating Θ-value, given 0.1% sequencing error and panel correction, is shown. All cases used the LAMARC error-aware correction. Except in the cases noted in the main text, each rejection rate was calculated from 100 LAMARC runs on data obtained from the same set of 100 independently generated trees. Successive panel sizes include the panel members of the smaller sizes.