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. 2013 Mar 22;8(3):e59621. doi: 10.1371/journal.pone.0059621

Figure 5. SalA inhibited the secretion of cytokines and collagen induced by MMP-9 CD.

Figure 5

(A) MMP-9 CD stimulated the secretion of IL-6, ICAM, sVCAM-1, TNF-α and SalA reversed the effects of MMP-9 CD partially. (B) SalA inhibited collagen secretion induced by MMP-9 CD. MMP-9/SalA(1) or MMP-9/SalA(10) denoted 1 µmol/L SalA or 10 µmol/L SalA was used to detect the inhibitory effects of SalA on MMP-9. *p<0.05, **p<0.01, ***p<0.001 versus Con; #p<0.05, ### p<0.001 versus MMP-9.