Skip to main content
. 2013 Mar 22;8(3):e60086. doi: 10.1371/journal.pone.0060086

Figure 5. MSKs promote IL-10 transcription.

Figure 5

Wild type and MSK1/2 knockout BMDMs were isolated and stimulated with either 200 µg/ml of zymosan (A, B, C), 10 µg/ml curdlan (D, E, F) or 200 µg/ml of depleted zymosan (Dep Zym, G, H, I) for the indicated times. IL-10 protein levels secreted into the media were measured (A, D, G) and IL-10 mRNA (B, E, H) or IL-10 1° transcript (C, F, I) induction determined by qPCR. Error bars represent the standard deviation of independent cultures from 4 mice per genotype. P values (Student's t-test) of less than 0.05 are indicated by * and less than 0.01 by **. ns indicates a p value of more than 0.05.