Table 2. Comparison of S. aureus Bacteremia Patients with and without Infectious Disease Consultation.
| Variable | Infectious diseases consultation | P | |
|---|---|---|---|
| Yes (n=111) | No (n=230) | ||
| Age, years, median (range) | 56 (23-95) | 56 (22-92) | .67 |
| Female gender | 55 (50) | 97 (42) | .20 |
| White race | 75 (68) | 121 (53) | .01 |
| Congestive heart failure | 28 (25) | 35 (15) | .04 |
| Coronary artery disease | 31 (28) | 49 (21) | .22 |
| COPD | 17 (15) | 37 (16) | .86 |
| Renal function | |||
| Normal | 90 (81) | 153 (67) | Ref |
| CRF without dialysis | 8 (7) | 19 (8) | .53 |
| CRF with dialysis | 13 (12) | 58 (26) | <.01 |
| Malignancy | 18 (16) | 67 (29) | .01 |
| Chronic skin disease | 7 (6) | 12 (5) | .80 |
| HIV | 8 (7) | 4 (2) | .02 |
| Peripheral vascular disease | 7 (6) | 16 (7) | 1.0 |
| Diabetes mellitus | 32 (29) | 79 (34) | .33 |
| Systemic corticosteroid use last 28 days | 15 (14) | 34 (15) | .87 |
| Liver cirrhosis | 6 (5) | 22 (10) | .21 |
| History of intravenous drug use | 11 (10) | 13 (6) | .18 |
| History of smoking | 49 (44) | 133 (58) | .02 |
| Alcohol use | 33 (30) | 62 (27) | .61 |
| Any transplant | 9 (8) | 17 (8) | .83 |
| Surgery during hospitalization | 16 (14) | 29 (13) | .73 |
| Prosthetic joint | 17 (15) | 12 (4) | <.01 |
| Other orthopedic hardware | 18 (16) | 5 (2) | <.01 |
| Vascular graft | 10 (9) | 38 (17) | .07 |
| Prosthetic valve | 9 (8) | 0 | <.01 |
| Cardiac device | 16 (14) | 14 (6) | .01 |
| ICU admission within 48 hours after the first positive blood culture | 35 (31) | 75 (33) | .90 |
| Central venous catheterization at the time of the first positive blood culture | 63 (57) | 168 (73) | <.01 |
| MRSA | 58 (52) | 127 (55) | .64 |
| Onset | |||
| Community-associated | 21 (19) | 16 (7) | Ref |
| Healthcare-associated community onset | 61 (55) | 135 (59) | <.01 |
| Healthcare-associated hospital onset | 29 (26) | 79 (34) | <.01 |
| Metastatic infection | 41 (37) | 18 (8) | <.01 |
| Prolonged bacteremia* | 43 (39) | 50 (22) | <.01 |
Note. COPD, chronic obstructive pulmonary disease; CRF, chronic renal failure; HIV, human immunodeficiency virus; ICU, intensive care unit; MRSA, methicillin-resistant S. aureus; Ref, reference.
*
See methods for definition.