Table 1.

Evaluation of Replication Competent Virus and Vector Sequences in Ewes Receiving Lentiviral-Treated Embryos; All samples were negative by the respective assay.

	Number of Animals	p24 ELISA	Blood VSV- G qPCR	Organ VSV- G qPCR	Blood Vector qPCR	Organ Vector qPCR
Surrogates without offspring	10	10	10	63	10	62
Surrogates with negative offspring	23	23	23	126	23	123
Surrogates with at least one positive offspring	24	22	24	99	24	96
Total	57	55	57	288	57	281

Organs include from liver, lung, ovary, spleen, muscle, heart, skin, kidney, mammary gland and surrogate uterus. Details are provides in supplemental Tables 1 and 2.