Table 2.
Bisphosphonates: potency, administration and main indications
Type of BPs | Potency | Administration | Main Indications |
---|---|---|---|
NNBPs | |||
Etidronate |
1 |
Oral |
Osteoporosis, Paget’s disease of bone |
Clodronate |
10 |
Oral/ Intravenous |
Osteoporosis, Paget’s disease of bone |
Tiludronate |
10 |
Oral |
Paget’s disease of bone |
NBPs | |||
Pamidronate |
100 |
Intravenous |
Osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma, Paget’s disease of bone |
Alendonate |
500 |
Oral |
Osteoporosis, Paget's disease of bone |
Ibandronate |
1000 |
Oral, Intravenous |
Osteoporosis |
Risedronate |
2000 |
Oral, Intravenous |
Osteoporosis, Paget’s disease of bone, osteolytic lesions of multiple myeloma, hypercalcemia of malignancy |
Zoledronate | 10000 | Intravenous | Osteolytic lesions of multiple myeloma and metastases from solid tumors, hypercalcemia of malignancy |