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. 2013 Jan 14;5:1. doi: 10.1186/2045-824X-5-1

Table 2.

Bisphosphonates: potency, administration and main indications

Type of BPs Potency Administration Main Indications
NNBPs
Etidronate
1
Oral
Osteoporosis, Paget’s disease of bone
Clodronate
10
Oral/ Intravenous
Osteoporosis, Paget’s disease of bone
Tiludronate
10
Oral
Paget’s disease of bone
NBPs
Pamidronate
100
Intravenous
Osteolytic bone metastases of breast cancer and osteolytic lesions of multiple myeloma, Paget’s disease of bone
Alendonate
500
Oral
Osteoporosis, Paget's disease of bone
Ibandronate
1000
Oral, Intravenous
Osteoporosis
Risedronate
2000
Oral, Intravenous
Osteoporosis, Paget’s disease of bone, osteolytic lesions of multiple myeloma, hypercalcemia of malignancy
Zoledronate 10000 Intravenous Osteolytic lesions of multiple myeloma and metastases from solid tumors, hypercalcemia of malignancy