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. 2013 Mar 19;13:50. doi: 10.1186/1471-230X-13-50

Table 2.

Potential RR autoantibody targets indentified on a protein/peptide microarray

Clone ID Description Structure/function Reactivity*
MPMGp800M18568
MPMGp800E06542
MPMGp800H07541
MPMGp800P08580
Homo sapiens MAZI;
Alternate name: Purine- binding transcription factor (ZF87) (ZIF87). Source: SWISSPROT; Acc:P56270
C2H2-type zinc fingers; transcription initiation and termination; purine metabolism [39,40]
4+
MPMGp800O22578
Homo sapiens VDAC1
Outer mitochondrial membrane; role in apoptosis and cancer; interacts with amyloid and tau role in Alzheimer’s [41-43]
3+
MPMGp800A24548
Homo sapiens ARM and sterile alpha motif domain containing 6 (ANKS6)
ARM participate in protein folding and found in ~6% of eukaryotic proteins [44,45]
2+
MPMGp800L08582
Homo sapiens ARP1 – homolog A (ACTR1A)
Major subunit of dynactin; molecular motor component; binds ATP and NuMA [46,47]
3+
MPMGp800K12532
MPMGp800L22599
MPMGp800E04593
Unknown proteins Unknown 2 – 3+

*Reactivity = the intensity of immunoreactivity with proteins on the microarray which were graded from 0 (no reactivity) to 4 (high intensity).

Abbreviations: ARM, ankyrin repeat motif; ARP, actin-related protein; ATP, adenosine triphospate; MAZI, Myc-associated zinc finger protein; NuMA, nuclear mitotic apparatus (NuMA) protein; VDAC1, voltage-dependent anion channel 1.