Figure 1. SEC^PBMC leads to enhanced wound closure and re-epithelialization.

(A) Wound areas were measured during the first 3 days after wounding. Treatment with SEC^PBMC significantly enhanced wound closure. Error bars represent one standard deviation calculated from 15 animals for each set of values (*: p<0.05). (B) Representative photographs from mouse wounds (n = 15 from each group) immediately after wounding and at day 7 after wounding are shown. (C) H&E staining of wounds treated with medium or SEC^PBMC 7 days after wounding is shown. While medium treated wounds still show a thick crust and little re-epithelialization, SEC^PBMC treated wounds are fully re-epithelialized. C  =  crust, E  =  newly formed epidermis, G  =  granulation tissue. Scale bars: 100 µm. One representative animal of 15 is shown.