Table 4. Analysis of the 42 discordant cases between OSNA and histology.
Number of SLNs | Size of metastasis | OSNA Results | OSNA Copies/µl | Molecular Subtype | ALND Results |
Histology Results: negative | |||||
2 | − | + | ≥2500≤3200 | HS | + |
1 | − | + | 3600 | LA | + |
3 | − | + | ≥6300≤1700 | HS | − |
3 | − | + | ≥300≤540 | LB | − |
2 | − | + | ≥270≤830 | TN | − |
14 | − | + | ≥280≤1400 | LA | − |
3 | − | ++ | ≥8000≤21000 | LA | + |
Total 28 | |||||
Histology Results: micrometastasis | |||||
7 | 0.1–1 mm | − | <250 | LA | − |
Histology Results: macrometastasis | |||||
2 | 2.5 mm | − | <250 | LA | + |
2 | 3.0 mm | − | <250 | LA | − |
3 | 2.5–3 mm | − | <250 | HS | − |
Total 14 |
OSNA: one step nucleic acid amplification; SLN: sentinel lymph node; HS: HER2 subtype; LA: Luminal A; LB: Luminal B; TN: Triple Negative; ALND: axillary lymph node dissection.