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. 2013 Mar 22;8(3):e58823. doi: 10.1371/journal.pone.0058823

Table 4. Analysis of the 42 discordant cases between OSNA and histology.

Number of SLNs Size of metastasis OSNA Results OSNA Copies/µl Molecular Subtype ALND Results
Histology Results: negative
2 + ≥2500≤3200 HS +
1 + 3600 LA +
3 + ≥6300≤1700 HS
3 + ≥300≤540 LB
2 + ≥270≤830 TN
14 + ≥280≤1400 LA
3 ++ ≥8000≤21000 LA +
Total 28
Histology Results: micrometastasis
7 0.1–1 mm <250 LA
Histology Results: macrometastasis
2 2.5 mm <250 LA +
2 3.0 mm <250 LA
3 2.5–3 mm <250 HS
Total 14

OSNA: one step nucleic acid amplification; SLN: sentinel lymph node; HS: HER2 subtype; LA: Luminal A; LB: Luminal B; TN: Triple Negative; ALND: axillary lymph node dissection.