Table 1.

Final body weight, body weight gain, and water consumption of rats treated with different doses of the C. langsdorffii extract and/or DMH and their respective controls, for the comet assay

Treatments (mg/kg)	Final body weight (g)*	Body weight gain (g)*	Water consumption*a
EDTA	166.8 ± 11.6	54.5 ± 7.9	36.9 ± 5.6
DMSO	170.6 ± 11.0	51.1 ± 6.3	41.5 ± 4.7
80	167.5 ± 11.0	54.6 ± 5.8	40.6 ± 7.4
DMH	165.0 ± 11.3	52.6 ± 7.4	37.2 ± 6.5
DMSO + DMH	168.1 ± 10.4	56.6 ± 7.6	44.6 ± 12.3
20 + DMH	167.1 ± 11.4	52.3 ± 9.3	37.9 ± 5.8
40 + DMH	168.1 ± 11.3	49.3 ± 6.3	37.5 ± 6.8
80 + DMH	169.6 ± 10.2	53.3 ± 6.9	45.5 ± 7.2

EDTA, vehicle control; DMH, 1,2-dimethylhydrazine (40 mg/kg); DMSO, dimethylsulfoxide (0.6 g/kg). The numbers 20, 40, and 80 correspond to the extract dose in mg/kg.

*Values are the mean ± standard deviation.

^aWater consumption calculated in mL per animal per day.