Table 2.

Final body weight, body weight gain, and water consumption of rats treated with different doses of the C. langsdorffii extract and/or DMH and their respective controls, for the aberrant crypt foci (ACF) assay

Treatments (mg/kg)	Final body weight (g)*	Body weight gain (g)*	Water consumption*a
EDTA	326.8 ± 12.5	215.6 ± 11.9	37.5 ± 6.8
DMSO	335.6 ± 11.2	214.5 ± 11.7	37.5 ± 4.4
80	325.5 ± 12.8	219.0 ± 11.5	37.5 ± 6.8
DMH	321.8 ± 10.1	222.5 ± 10.7	37.9 ± 5.8
DMSO + DMH	334.3 ± 11.3	223.5 ± 11.0	45.5 ± 7.2
20 + DMH	334.5 ± 10.9	224.3 ± 10.8	37.2 ± 6.5
40 + DMH	341.8 ± 11.5	221.8 ± 11.1	44.6 ± 12.3
80 + DMH	340.5 ± 12.1	225.5 ± 11.8	55.0 ± 18.7

EDTA, vehicle control; DMH, 1,2-dimethylhydrazine (160 mg/kg); DMSO, dimethylsulfoxide (0.6 g/kg). The numbers 20, 40, and 80 correspond to the extract dose in mg/kg.

*Values are the mean ± standard deviation.

^aWater consumption calculated in mL per animal per day.