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. 2013 Mar 11;7:20. doi: 10.1186/1752-0509-7-20

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Copyright ©2013 Yin and Voit; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Monte-Carlo simulation results for evaluating the functional effectiveness of the Nox1 disassembly system against three experimental observations. Top-left: 6964 points (corresponding to combinations of proteolytic and recycling flux magnitudes) are retained after screening against the first experimental observation. Top-right: 1476 points are retained after screening against the second experimental observation; Bottom-left: 5460 points are retained after screening against the third experimental observation; Bottom-right: 825 points are retained after screening against all three experimental observations. See text for further details on specific experimental conditions.