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Simplified examples illustrating the need for a proper distribution of Nox1 subunits
| Subunit distribution in RtRS | Responsiveness to representative signals |
|---|---|
| [p47phox] = 0; [Rac1GDP] = 0; |
No response to S1, S2, or S1 &S2 |
| [p47phox] = 0; [Rac1GDP] = 1; |
Response to S2, and S1 &S2, but no response to S1 |
| [p47phox] = 1; [Rac1GDP] = 0; |
Response to S1, and S1 &S2, but no response to S2 |
| [p47phox] = 1; [Rac1GDP] = 1; | Response only to S1 &S2, but not to S1 or S2 |
