Table 2. Linear regression models testing the effects of PER2 rs56013859 genotype, severe negative life events and their interaction on drinking measures in young adult regular drinkers (n = 131).
Drinking measures1 | rs56013859 genotype | Severe negative life events | rs56013859 × severe negative life events | |||
B | p | B | p | B | p | |
Number of drinking days2 | −2.929 (1.450) | .046 | 0.276 (0.205) | .181 | 0.110 (0.628) | .861 |
Total number of drinks2 | −9.871 (10.215) | .336 | 6.506 (1.443) | <.001 | −2.704 (4.416) | .541 |
AUDIT score | −0.437 (0.795) | .584 | 0.572 (0.112) | <.001 | −0.786 (0.337) | .021 |
Note: All models adjusted for sex and age. Main effects of genotype and severe negative life events were entered in a first step, followed by the interaction term in a second step.
Unstandardized regression coefficients from linear regression (standard errors);
referring to the last 45 days.