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. 2013 Mar 22;8(3):e59121. doi: 10.1371/journal.pone.0059121

Table 4. Hazard ratios and 95% confidence intervals for men and women calculated by Cox regression.

Event SUA Model 1 Model 2 Model 3 Model 4
All-cause mortality, men Q1 1 (ref) 1 (ref) 1 (ref) 1 (ref)
Q2 1.01 (0.781.30) 0.96 (0.751.24) 0.90 (0.701.16) 0.90 (0.691.16)
Q3 1.15 (0.901.47) 1.08 (0.841.39) 0.95 (0.741.22) 0.97 (0.751.25)
Q4 1.55 (1.23–1.96) * 1.47 (1.16–1.85) * 1.08 (0.851.38) 1.10 (0.851.42)
All–cause mortality, women Q1 1 (ref) 1 (ref) 1 (ref) 1 (ref)
Q2 0.82 (0.551.23) 0.80 (0.541.20) 0.74 (0.491.10) 0.75 (0.501.13)
Q3 1.11 (0.761.61) 1.08 (0.731.56) 0.93 (0.641.35) 0.88 (0.601.30)
Q4 2.35 (1.70–3.25) * 2.17 (1.57–3.00) * 1.62 (1.16–2.25) * 1.47 (1.02–2.12) *

Cut off points for quartiles: see Table 2. Ref = reference. Hazard ratios (95% confidence intervals).

*

Hazard ratios with p-values less than 0.05 are written in bold letters.

Model 1: uric acid.

Model 2: model 1+ age.

Model 3: model 2+ baseline serum creatinine and diuretics use.

Model 4: model 3+ baseline values of cholesterol, HDL-C, LDL-C, BMI, glucose, triglyceride, history of only diabetes/both diabetes and cardiovascular disease/only cardiovascular disease, history of congestive heart failure, systolic blood pressure, diastolic blood pressure, waist-hip ratio, tobacco use, alcohol use, beta-blocker use, statin use, aspirin use and sibutramine use.