Table 4. Hazard ratios and 95% confidence intervals for men and women calculated by Cox regression.
Event | SUA | Model 1 | Model 2 | Model 3 | Model 4 |
All-cause mortality, men | Q1 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
Q2 | 1.01 (0.78–1.30) | 0.96 (0.75–1.24) | 0.90 (0.70–1.16) | 0.90 (0.69–1.16) | |
Q3 | 1.15 (0.90–1.47) | 1.08 (0.84–1.39) | 0.95 (0.74–1.22) | 0.97 (0.75–1.25) | |
Q4 | 1.55 (1.23–1.96) * | 1.47 (1.16–1.85) * | 1.08 (0.85–1.38) | 1.10 (0.85–1.42) | |
All–cause mortality, women | Q1 | 1 (ref) | 1 (ref) | 1 (ref) | 1 (ref) |
Q2 | 0.82 (0.55–1.23) | 0.80 (0.54–1.20) | 0.74 (0.49–1.10) | 0.75 (0.50–1.13) | |
Q3 | 1.11 (0.76–1.61) | 1.08 (0.73–1.56) | 0.93 (0.64–1.35) | 0.88 (0.60–1.30) | |
Q4 | 2.35 (1.70–3.25) * | 2.17 (1.57–3.00) * | 1.62 (1.16–2.25) * | 1.47 (1.02–2.12) * |
Cut off points for quartiles: see Table 2. Ref = reference. Hazard ratios (95% confidence intervals).
Hazard ratios with p-values less than 0.05 are written in bold letters.
Model 1: uric acid.
Model 2: model 1+ age.
Model 3: model 2+ baseline serum creatinine and diuretics use.
Model 4: model 3+ baseline values of cholesterol, HDL-C, LDL-C, BMI, glucose, triglyceride, history of only diabetes/both diabetes and cardiovascular disease/only cardiovascular disease, history of congestive heart failure, systolic blood pressure, diastolic blood pressure, waist-hip ratio, tobacco use, alcohol use, beta-blocker use, statin use, aspirin use and sibutramine use.