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. Author manuscript; available in PMC: 2014 Mar 19.
Published in final edited form as: Anal Chem. 2013 Feb 28;85(6):3198–3206. doi: 10.1021/ac303383c

Figure 6.

Figure 6

(A) A heatmap displaying the relative selectivity of ATP/GTP towards each possible binding motif of kinases. Dark blue and white indicate significant ATP-binding preference with high RATP/GTP ratio and significant GTP-binding preference with small RATP/GTP ratio, respectively (See scale bar above the heatmap). (B) Protein kinases were mapped to the human kinome dendrogram with color annotation to specify the motif with the highest RATP/GTP ratio. Red, green and blue represent kinases with HRDxKxxN, VAxK, and GxxxxGK motifs, respectively.