Table 4.
Mean age of flies overexpressing dPrx4
| Overexpression level and genotype | Age (d) | Percentage |
|
|---|---|---|---|
| Vs. transgene/+ | Vs. driver/+ | ||
| High level | |||
| UAS-dPrx4-A/+ | 57.6; 58.2 | ||
| UAS-dPrx4-B/+ | 54.1; 53.9 | ||
| UAS-dPrx4-C/+ | 64.5; 55.3 | ||
| +/Arm | 45.8; 53.1 | ||
| UAS-dPrx4-A/Arm | 56.8; 54.3 | 98; 93* | 124;* 102 |
| UAS-dPrx4-B/Arm | 57.4; 57.2 | 106; 107 | 125;* 108* |
| UAS-dPrx4-C/Arm | 72.3; 59.7 | 112;* 108* | 158;* 112* |
| Low level | |||
| UAS-dPrx4-A/+ | 50.1; 59.5 | ||
| UAS-dPrx4-B/+ | 70.2; 51.6 | ||
| UAS-dPrx4-C/+ | 56.8; 62.7 | ||
| +/Da | 49.6; 60.4 | ||
| UAS-dPrx4-A/Da | 10.3; 30.5 | 21;* 51* | 21;* 51* |
| UAS-dPrx4-B/Da | 26.4; 21.1 | 38;* 41* | 53;* 35* |
| UAS-dPrx4-C/Da | 40.1; 32,8 | 71;* 52* | 81;* 54* |
Age column lists values obtained for 2 independent cohorts. Percentage columns list overall percentage of the experimentals vs. the transgene/+ and driver/+ controls.
P < 0.05 vs. control flies, determined by log-rank test.