Table 1.
Clinical data for human brain tissue samples
| Case no. | HIV-1 infection | Age (yr) | Gender | Viral load (plasma) | CD4 cell count | Neurocognitive assessment | Antiretroviral therapy | Pathological evidence of encephalitis |
|---|---|---|---|---|---|---|---|---|
| 1 (3015) | Seronegative control | 64 | Female | NA | 118 | Neuropsychological impairment or dementia due to other cause | None | HIV−, PML |
| 2 (ID: 7101958083) | Seronegative control | 46 | Male | NA | NA | Unable to reliably assign neurocognitive diagnosis | None | Normal |
| 3 (ID: 7102308387) | Seronegative control | 49 | Male | NA | NA | Unable to reliably assign neurocognitive diagnosis | None | Normal |
| 4 (4084) | HIV-E | 46 | Male | 40,519 | 18 | Neuropsychological impairment or dementia due to other cause | None | HIV-E, microglial nodule encephalitis |
| 5 (ID: 7100616568) | HIV-E | 32 | Male | 489,796 | 77 | Possible HAD | 3TC, ABC, EFV | HIV-E |
| 6 (ID: 7100107766) | HIV-E | 38 | Male | 1,843 | 43 | Possible HAD | EFV, NVP | HIV-E |