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Novel Agents currently in clinical trials for Diffuse Large B Cell Lymphoma
| Mechanism of Action | Drug(s) |
|---|---|
| Antibodies against VEGF | Bevacizumab |
| PKC-β inhibitor | Enzastaurin |
| Anti-CD22 | Epratuzumab, |
| mTOR inhibitor | Everolimus, Temsirolimus |
| Immunomodulatory agents | Lenalidomide |
| Syk-kinase inhibitor | Fostamatinib |
| NEDD8 activating enzyme inhibitor | MLN4924 |
| Proteasone Inhibitor | Bortezomib, Carfilzomib |
| Histone Deacetylase Inhibitor | Panobinostat, MGCD013 |
