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. Author manuscript; available in PMC: 2013 Mar 23.
Published in final edited form as: Nat Commun. 2012 Mar 27;3:755. doi: 10.1038/ncomms1754

Figure 6. Increased inflammasome activation in annexin A2 knock out mice.

Figure 6

(a) ultrasctructural analysis of annexin A2 + / + DC. Bar correspond to 2 μm. (b) ultrasctructural analysis of annexin A2 – / – DC. Bar correspond to 2 μm. (c) FACs analysis of DC surface markers on annexin A2 + / + DC. (d) FACs analysis of DC surface markers on annexin A2 – / –DC. (e) Western blot analysis and (f) densitometry analysis of cytosolic cathepsin B in control CTR and WD-treated DC. The mean and s.e.m. of three experiments is shown (P < 0.001, ANOVA, Tukey). (g) ELISA for IL-1β secretion from untreated and WD-treated DC (12 h), and from wild type DC and DC deficient in PGN (a TLR2 agonist). The mean and s.e.m. of four experiments is shown (P < 0.001, ANOVA, Tukey).